Anti-KIF4A/4B Antibody Picoband®

SKU: A04486-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: KIF4A/4B

Specificity:

Background: Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene. This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.

Immunogen: E.coli-derived human KIF4A/4B recombinant protein (Position: K729-D1174).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Ha, M. J., Yoon, J., Moon, E., Lee, Y. M., Kim, H. J., Kim, W. Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization. Cytogenet. Cell Genet. 88: 41-42, 2000. 2. Kim, W., Tang, Y., Okada, Y., Torrey, T. A., Chattopadhyay, S. K., Pfleiderer, M., Falkner, F. G., Dorner, F., Choi, W., Hirokawa, N., Morse, H. C., III. Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein. J. Virol. 72: 6898-6901, 1998. 3. Kurasawa, Y., Earnshaw, W. C., Mochizuki, Y., Dohmae, N., Todokoro, K. Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. EMBO J. 23: 3237-3248, 2004.

Uniprot ID: O95239/Q2VIQ3

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 140 kDa

Calculated Molecular Weight: 43696 MW

Gene ID: 24137/285643

Protein Name: ATP-dependent RNA helicase DDX19A/B

Gene Full Name: kinesin family member 4A/4B

Synonyms: KIF4A; KIF4; Chromosome-associated kinesin KIF4A; Chromokinesin-A; KIF4B; Chromosome-associated kinesin KIF4B; Chromokinesin-B