Anti-Keratocan/KTN/Kera Antibody Picoband®

SKU: A07712-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: Kera

Specificity:

Background: Keratocan (KTN) also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).

Immunogen: E.coli-derived mouse Keratocan/KTN/Kera recombinant protein (Position: R73-K115).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Dudakova, L., Palos, M., Hardcastle, A. J., Liskova, P. Corneal endothelial findings in a Czech patient with compound heterozygous mutations in KERA. (Letter) Ophthalmic Genet. 35: 252-254, 2014. 2. Funderburgh, J. L., Perchellet, A. L., Swiergiel, J., Conrad, G. W., Justice, M. J. Keratocan (Kera), a corneal keratan sulfate proteoglycan, maps to the distal end of mouse chromosome 10. Genomics 52: 110-111, 1998. 3. Khan, A. O., Al-Saif, A., Kambouris, M. A novel KERA mutation associated with autosomal recessive cornea plana. Ophthal. Genet. 25: 147-152, 2004. Note: Erratum: Ophthal. Genet. 25: 289 only, 2004; Ophthal. Genet. 26: 195 only, 2005.

Uniprot ID: O35367

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 41 kDa

Calculated Molecular Weight: 49229 MW

Gene ID: 16545

Protein Name: Keratocan

Gene Full Name: keratocan

Synonyms: keratocan; CNA2; KTN; SLRR2B; KERA