Anti-JAK2 Monoclonal Antibody

SKU: M00027

Size: 100 μl

Storage: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Form: Liquid

Reactivity: Human,Mouse,Rat

Applications: IP,IF,IHC,ICC,WB

Application Details: WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
IP 1:50-100

Gene Name: JAK2

Specificity:

Background:

Immunogen: A synthesized peptide derived from human JAK2 Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

Clonality: Monoclonal

Contents: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Affinity-chromatography

Reconstitution:

Reference:

Uniprot ID: O60674

Host: Rabbit

Concentration: 0.5mg/ml

Conjugate:

Cross Reactivity:

Isotype: Rabbit IgG

Phospho_site:

Clone Number: Clone: COG-10

Observed Molecular Weight: 131 kDa

Calculated Molecular Weight: 88068 MW

Gene ID: 3717

Protein Name: Tyrosine-protein kinase JAK2

Gene Full Name: Janus kinase 2

Synonyms: Janus kinase 2; JTK10; JAK2