Anti-ITPK1 Antibody Picoband®

SKU: A09106-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ITPK1

Specificity:

Background: Inositol-tetrakisphosphate 1-kinase is an enzyme that in humans is encoded by the ITPK1 gene. This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X.

Immunogen: E.coli-derived human ITPK1 recombinant protein (Position: Q25-Q414). Human ITPK1 shares 92.7% amino acid (aa) sequence identity with mouse ITPK1.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Gross, M. B. Personal Communication. Baltimore, Md. 7/25/2014. 2. Wilson, M. P., Majerus, P. W. Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning, and expression of the recombinant enzyme. J. Biol. Chem. 271: 11904-11910, 1996. 3. Yang, X., Shears, S. B. Multitasking in signal transduction by a promiscuous human ins(3,4,5,6)P4 1-kinase/Ins(1,3,4)P3 5/6-kinase. Biochem. J. 351: 551-555, 2000.

Uniprot ID: Q13572

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 42 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 3705

Protein Name: Inositol-tetrakisphosphate 1-kinase

Gene Full Name: inositol-tetrakisphosphate 1-kinase

Synonyms: Ins(1; 3; 4)P(3) 5/6 kinase; ITPK1; ITRPK1