Anti-Integrin alpha-9/ITGA9 Antibody Picoband®

SKU: A06851-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ITGA9

Specificity:

Background: Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene. This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.

Immunogen: E.coli-derived human Integrin alpha-9/ITGA9 recombinant protein (Position: Q526-Q1035). Human ITGA9 shares 89.6% amino acid (aa) sequence identity with mouse ITGA9.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Daigo, Y., Isomura, M., Nishiwaki, T., Tamari, M., Ishikawa, S., Kai, M., Murata, Y., Takeuchi, K., Yamane, Y., Hayashi, R., Minami, M., Fujino, M. A., Hojo, Y., Uchiyama, I., Takagi, T., Nakamura, Y. Characterization of a 1200-kb genomic segment of chromosome 3p22-p21.3. DNA Res. 6: 37-44, 1999. 2. Erle, D. J., Sheppard, D., Breuss, J., Ruegg, C., Pytela, R. Novel integrin alpha and beta subunit cDNAs identified in airway epithelial cells and lung leukocytes using the polymerase chain reaction. Am. J. Resp. Cell Molec. Biol. 5: 170-177, 1991. 3. Hibi, K., Yamakawa, K., Ueda, R., Horio, Y., Murata, Y., Tamari, M., Uchida, K., Takahashi, T., Nakamura, Y., Takahashi, T. Aberrant upregulation of a novel integrin alpha subunit gene at 3p21.3 in small cell lung cancer. Oncogene 9: 611-619, 1994.

Uniprot ID: Q13797

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 120 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 3680

Protein Name: Integrin alpha-9

Gene Full Name: integrin subunit alpha 9

Synonyms: Alpha RLC; ITGA4L; ITGA9; RLC