Anti-IL27 Antibody Picoband®

SKU: A00857-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Rat

Applications: ELISA,WB

Application Details: Western blot,0.1-0.5μg/ml
ELISA,0.1-0.5μg/ml

Gene Name: Il27

Specificity: No cross reactivity with other proteins.

Background: Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Immunogen: E. coli-derived mouse IL27 recombinant protein (Position: F29-S234).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Meka, Rakeshchandra R.; Venkatesha, Shivaprasad H.; Dudics, Steven; Acharya, Bodhraj; Moudgil, Kamal D. IL-27-induced modulation of autoimmunity and its therapeutic potential. Autoimmunity Reviews. 14 (12): 1131–1141. 2. Yoshimoto, Takayuki; Chiba, Yukino; Furusawa, Jun-Ichi; Xu, Mingli; Tsunoda, Ren; Higuchi, Kaname; Mizoguchi, Izuru (2015-09-01). Potential clinical application of interleukin-27 as an antitumor agent. Cancer Science. 106 (9): 1103–1110.

Uniprot ID: Q8K3I6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 29 kDa

Calculated Molecular Weight:

Gene ID: 246779

Protein Name: Interleukin-27 subunit alpha

Gene Full Name: interleukin 27

Synonyms: IL 27; IL 27 A; IL 27 subunit alpha; IL 27A; IL27; IL-27; IL27 A; IL27A; IL27p28; IL30; interleukin 27; Interleukin 27 subunit alpha; p28