Anti-IL18 binding protein/Il18bp Antibody Picoband®

SKU: A07261-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: ELISA (Cap),WB

Application Details: Western blot, 0.1-0.5μg/ml
ELISA (Cap), 1-5μg/ml

Gene Name: Il18bp

Specificity: No cross reactivity with other proteins.

Background: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Immunogen: E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: IL18BP interleukin 18 binding protein. 2. Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M (Mar 1999). Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity. 10 (1): 127–36.

Uniprot ID: Q9Z0M9

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 43 kDa

Calculated Molecular Weight: 67166 MW

Gene ID: 16068

Protein Name: Interleukin-18-binding protein

Gene Full Name: interleukin 18 binding protein

Synonyms: IL 18BP; IL18BP; IL-18BP; IL18BPa; interleukin 18 binding protein; Tadekinig alfa