Anti-IL-3RB/Csf2rb Antibody Picoband®

SKU: A02219-3

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: ELISA,Flow Cytometry,IHC,WB

Application Details: Western blot, 0.25-0.5μg/ml, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Rat
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Mouse, Rat
ELISA, 0.1-0.5μg/ml, -

Gene Name: Csf2rb

Specificity: No cross reactivity with other proteins.

Background: Cytokine receptor common subunit beta is a protein that in humans is encoded by the CSF2RB gene. It is mapped to 15 E1; 15 37.36 cM. The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).

Immunogen: E.coli-derived mouseIL-3RB/Csf2rb recombinant protein (Position: A28-Q891).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. D'Andrea, R., Harrison-Findik, D., Butcher, C. M., Finnie, J., Blumbergs, P., Bartley, P., McCormack, M., Jones, K., Rowland, R., Gonda, T. J., Vadas, M. A. Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice. J. Clin. Invest. 102: 1951-1960, 1998. 2. D'Andrea, R., Rayner, J., Moretti, P., Lopez, A., Goodall, G. J., Gonda, T. J., Vadas, M. A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity. Blood 83: 2802-2808, 1994. 3. Dirksen, U., Hattenhorst, U., Schneider, P., Schroten, H., Gobel, U., Bocking, A., Muller, K.-M., Murray, R., Burdach, S. Defective expression of granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 receptor common beta chain in children with acute myeloid leukemia associated with respiratory failure. Blood 92: 1097-1103, 1998.

Uniprot ID: P26955

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 120 kDa

Calculated Molecular Weight: 38160 MW

Gene ID: 12983

Protein Name: Cytokine receptor common subunit beta

Gene Full Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

Synonyms: CD131; CDw131; CSF2RB; IL3RB; IL5RB