Anti-IER3 Antibody Picoband®

SKU: A04014-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,Flow Cytometry

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Gene Name: IER3

Specificity:

Background: This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IER3. Human IER3 shares 85% amino acid (aa) sequence identity with mouse IER3.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Akilov, O. E., Ustyugova, I. V., Zhi, L., Hasan, T., Wu, M. X. Enhanced susceptibility to Leishmania infection in resistant mice in the absence of immediate early response gene X-1. J. Immun. 183: 7994-8003, 2009. 2. Charles, C. H., Yoon, J. K., Simske, J. S., Lau, L. F. Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein. Oncogene 8: 797-801, 1993. 3. Kondratyev, A. D., Chung, K.-N., Jung, M. O. Identification and characterization of a radiation-inducible glycosylated human early-response gene. Cancer Res. 56: 1498-1502, 1996.

Uniprot ID: P46695

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 23 kDa

Calculated Molecular Weight: 17 kDa

Gene ID: 8870

Protein Name: Radiation-inducible immediate-early gene IEX-1

Gene Full Name: immediate early response 3

Synonyms: IER3; DIF2; IEX1; PRG1; Radiation-inducible immediate-early gene IEX-1; Differentiation-dependent gene 2 protein; Protein DIF-2; Immediate early protein GLY96; Immediate early response 3 protein; PACAP-responsive gene 1 protein; Protein PRG1