Anti-IDI2 Antibody Picoband®

SKU: A11225

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: IDI2

Specificity:

Background: The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis.

Immunogen: E.coli-derived human ING2 recombinant protein (Position: Q6-K181). Human ING2 shares 96.6% amino acid (aa) sequence identity with mouse ING2.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Breitling, R., Laubner, D., Clizbe, D., Adamski, J., Krisans, S. K. Isopentenyl-diphosphate isomerases in human and mouse: evolutionary analysis of a mammalian gene duplication. J. Molec. Evol. 57: 282-291, 2003. 2. Clizbe, D. B., Owens, M. L., Masuda, K. R., Shackelford, J. E., Krisans, S. K. IDI2, a second isopentenyl diphosphate isomerase in mammals. J. Biol. Chem. 282: 6668-6676, 2007. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 8/28/2013.

Uniprot ID: Q9BXS1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 27 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 91734

Protein Name: Isopentenyl-diphosphate delta-isomerase 2

Gene Full Name: isopentenyl-diphosphate delta isomerase 2

Synonyms: IDI2; Isopentenyl-diphosphate delta-isomerase 2; Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2