Anti-Human APP Reference Antibody (Aducanumab, RUO)

SKU: HY235046

Size:100ug

Description:Aducanumab (brand name: Aduhelm) is an amyloid beta-directed monoclonal antibody that targets amyloid beta in the brains of people with Alzheimer’s to reduce its buildup. Aducanumab is a monoclonal antibody (a protein that helps your immune system target other proteins), and it is designed to help your body remove something called amyloid beta from the brain. Amyloid beta is an important protein involved in the progression of Alzheimer’s disease. Aducanumab is given intravenously (infused through a vein) monthly. Aducanumab does not cure Alzheimer’s disease, but one (of two) large clinical studies suggests that aducanumab may slow the progression of the earliest symptoms of Alzheimer’s disease.

Host species:Human

Tested applications:

Species reactivity:Human

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% purity as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG1-kappa

Applications:ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Target:AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Expression system:Mammalian Cells

Accession:P05067

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Reconstitution:

Background:

Alternative Names:BART, BIIB-037, 1384260-65-4

Clone ID:

Species:

Note:For research use only. Not suitable for clinical or therapeutic use.