Anti-HTRA4 Antibody Picoband®

SKU: A13079-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: HTRA4

Specificity:

Background: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.

Immunogen: E.coli-derived human HTRA4 recombinant protein (Position: A31-D464). Human HTRA4 shares 68.7% and 68.9% amino acid (aa) sequence identity with mouse and rat HTRA4, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Clausen, T., Southan, C., Ehrmann, M. The HtrA family of proteases: implications for protein composition and cell fate. Molec. Cell 10: 443-455, 2002. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/12/2007.

Uniprot ID: P83105

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 51 kDa

Calculated Molecular Weight:

Gene ID: 203100

Protein Name: Serine protease HTRA4

Gene Full Name: HtrA serine peptidase 4

Synonyms: HtrA serine peptidase 4; HTRA4; Probable serine protease HTRA4