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GeneBio Systems

Anti-GATB Antibody Picoband®

Anti-GATB Antibody Picoband®

A08058-1

£431.00 GBP
£431.00 GBP
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Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: GATB

Specificity:

Background: GATB allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).

Immunogen: E.coli-derived human GATB recombinant protein (Position: R113-E443). Human GATB shares 89.7% amino acid (aa) sequence identity with mouse GATB.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Friederich, M. W., Timal, S., Powell, C. A., Dallabona, C., Kurolap, A., Palacios-Zambrano, S., Bratkovic, D., Derks, T. G. J., Bick, D., Bouman, K., Chatfield, K. C., Damouny-Naoum, N., and 41 others. Pathogenic variants in glutamyl-tRNA(Gln) amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nature Commun. 9: 4065, 2018. Note: Electronic Article. 2. Gross, M. B. Personal Communication. Baltimore, Md. 11/30/2016. 3. Nagao, A., Suzuki, T., Katoh, T., Sakaguchi, Y., Suzuki, T. Biogenesis of glutaminyl-mt tRNA(Gln) in human mitochondria. Proc. Nat. Acad. Sci. 106: 16209-16214, 2009.

Uniprot ID: O75879

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 62 kDa

Calculated Molecular Weight:

Gene ID: 5188

Protein Name: Glutamyl-tRNA

Gene Full Name: glutamyl-tRNA amidotransferase subunit B

Synonyms: GATB; PET112; PET112L; HSPC199; Glutamyl-tRNA(Gln amidotransferase subunit B, mitochondrial; Glu-AdT subunit B; Cytochrome c oxidase assembly factor PET112 homolog

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