Anti-Flavin containing monooxygenase 4/FMO4 Antibody Picoband®

SKU: PA1883

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: IHC,WB

Application Details: Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Rat, Human
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Gene Name: FMO4

Specificity: No cross reactivity with other proteins.

Background: FMO4 (Flavin-containing monooxygenase 4) also known as FMO2, FORMERLY or FMO, ADULT LIVER FORM, is an enzyme that in humans is encoded by the FMO4 gene. By PCR analysis, Dolphin et al. (1992) mapped the FMO4 gene to chromosome 1. Southern blot hybridization with single exon probes demonstrated that human FMO4 and FMO1 are, in each case, the product of a single gene. Lawton et al. (1994) proposed a reclassification of mammalian FMOs. Under this system, FMO2 described by Dolphin et al. (1992) is now designated FMO4.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Flavin containing monooxygenase 4, different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Dolphin, C. T., Shephard, E. A., Povey, S., Smith, R. L., Phillips, I. R. Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family. Biochem. J. 287: 261-267, 1992. 2. Lawton, M. P., Cashman, J. R., Cresteil, T., Dolphin, C. T., Elfarra, A. A., Hines, R. N., Hodgson, E., Kimura, T., Ozols, J., Phillips, I. R., Philpot, R. M., Poulsen, L. L., Rettie, A. E., Shephard, E. A., Williams, D. E., Ziegler, D. M. A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities. Arch. Biochem. Biophys. 308: 254-257, 1994. 3. Phillips, I. R., Dolphin, C. T., Clair, P., Hadley, M. R., Hutt, A. J., McCombie, R. R., Smith, R. L., Shephard, E. A.The molecular biology of the flavin-containing monooxygenases of man. Chem. Biol. Interact. 96: 17-32, 1995.

Uniprot ID: P31512

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 95 kDa

Calculated Molecular Weight: 63343 MW

Gene ID: 2329

Protein Name: Dimethylaniline monooxygenase [N-oxide-forming] 4

Gene Full Name: flavin containing dimethylaniline monoxygenase 4

Synonyms: Dimethylaniline oxidase 4; FMO 4; FMO2; FMO4