Anti-CUX1 Antibody Picoband®

SKU: A01653-4

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: ELISA,Flow Cytometry,IHC,WB

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: CUX1

Specificity:

Background: The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen: E.coli-derived human CUX1 recombinant protein (Position: M1-E220).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Cubelos, B., Sebastian-Serrano, A., Beccari, L., Calcagnotto, M. E., Cisneros, E., Kim, S., Dopazo, A., Alvarez-Dolado, M., Redondo, J. M., Bovolenta, P., Walsh, C. A., Nieto, M. Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex. Neuron 66: 523-535, 2010. 2. Doan, R. N., Bae, B.-I., Cubelos, B., Chang, C., Hossain, A. A., Al-Saad, S., Mukaddes, N. M., Oner, O., Al-Saffar, M., Balkhy, S., Gascon G. G., The Homozygosity Mapping Consortium for Autism, Nieto, M., Walsh, C. A. Mutations in human accelerated regions disrupt cognition and social behavior. Cell 167: 341-354, 2016. 3. Gillingham, A. K., Pfeifer, A. C., Munro, S. CASP, the alternatively spliced product of the gene encoding the CCAAT-displacement protein transcription factor, is a Golgi membrane protein related to giantin. Molec. Biol. Cell. 13: 3761-3774, 2002.

Uniprot ID: P39880

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 200 kDa

Calculated Molecular Weight: 50514 MW

Gene ID: 1523

Protein Name: Homeobox protein cut-like 1

Gene Full Name: cut like homeobox 1

Synonyms: CUX1; CUTL1; Homeobox protein cut-like 1; CCAAT displacement protein; CDP; Homeobox protein cux-1