Anti-CDX2 Antibody Picoband®

SKU: A00877-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB

Application Details: Western blot, 0.25-0.5 μg/ml, Human

Gene Name: CDX2

Specificity:

Background: Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene. This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CDX2.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Aoki, K., Tamai, Y., Horiike, S., Oshima, M., Taketo, M. M. Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc(+/delta716) Cdx2(+/-) compound mutant mice. Nature Genet. 35: 323-330, 2003. 2. Chawengsaksophak, K., de Graaff, W., Rossant, J., Deschamps, J., Beck, F. Cdx2 is essential for axial elongation in mouse development. Proc. Nat. Acad. Sci. 101: 7641-7645, 2004. 3. Chawengsaksophak, K., James, R., Hammond, V. E., Kontgen, F., Beck, F. Homeosis and intestinal tumours in Cdx2 mutant mice. Nature 386: 84-87, 1997.

Uniprot ID: Q99626

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 45 kDa

Calculated Molecular Weight:

Gene ID: 1045

Protein Name: Forkhead box D1

Gene Full Name: caudal type homeobox 2

Synonyms: caudal type homeobox 2; Caudal type homeobox protein 2; CDX 3; CDX2; CDX-2; CDX3; Homeobox protein CDX 2