Anti-Cdc25c Antibody Picoband®

SKU: A01343-3

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5μg/ml, Rat
ELISA, 0.1-0.5μg/ml, -

Gene Name: Cdc25c

Specificity:

Background: M-phase inducer phosphatase 3is anenzymethat in humans is encoded by theCDC25Cgene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It s dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Immunogen: E.coli-derived mouse Cdc25c recombinant protein (Position: K24-Q447).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: CDC25C cell division cycle 25 homolog C (S. pombe). 2. Gould KL, Moreno S, Tonks NK, Nurse P (Feb 1991). Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase. Science 250 (4987): 1573–6. 3. Sartor H, Ehlert F, Grzeschik KH, et al. (1992). Assignment of two human cell cycle genes, CDC25C and CCNB1, to 5q31 and 5q12, respectively. Genomics 13(3): 911–2.

Uniprot ID: P48967

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 53 kDa

Calculated Molecular Weight:

Gene ID: 12532

Protein Name: M-phase inducer phosphatase 3

Gene Full Name: cell division cycle 25C

Synonyms: CDC25; CDC25C; M phase inducer phosphatase 3