Anti-CD89/FCAR Antibody Picoband®

SKU: PA1549

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml, Human

Gene Name: FCAR

Specificity: No cross reactivity with other proteins.

Background: FCAR, Receptor for Fc fragment of IGA, is also known as CD89. Human Fc-alpha receptor (FCAR) is present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. FCAR interacts with aggregated IgAs, such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is a glycoprotein of 50 to 100 kD, with diversity on different cell types. FCAR is mapped to 19q13.4. Human COS cells transfected with FCAR cDNA bind to IgA, but not IgG.

Immunogen: A synthetic peptide corresponding to a sequence in the middle of human CD89.

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Kremer, E. J., Kalatzis, V., Baker, E., Callen, D. F., Sutherland, G. R., Maliszewski, C. R.The gene for the human IgA Fc receptor maps to 19q13.4.Hum. Genet. 89: 107-108, 1992. 2. Maliszewski, C. R., March, C. J., Schoenborn, M. A., Gimpel, S., Shen, L.Expression cloning of a human Fc receptor for IgA.J. Exp. Med. 172: 1665-1672, 1990.

Uniprot ID: P24071

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 34 kDa

Calculated Molecular Weight: 32265 MW

Gene ID: 2204

Protein Name: Immunoglobulin alpha Fc receptor

Gene Full Name: Fc alpha receptor

Synonyms: CD89; FCAR; IgA Fc receptor