Anti-Alpha Tubulin/TUBA1C Antibody Picoband®

SKU: A03989-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human

Gene Name: Alpha Tubulin/TUBA1C

Specificity:

Background: Tubulin alpha-1C chain is a protein that in humans is encoded by the TUBA1C gene. TUBA1C is an 伪-tubulin isoform involved in mitosis, and its dysregulation has been implicated in tumor progression. There is still no clear understanding of its role in bladder urothelial carcinoma (BLCA).

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TUBA1C.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hu, X., Zhu, H., Chen, B., He, X., Shen, Y., Zhang, X., ... & Xu, X. (2022). The oncogenic role of tubulin alpha-1c chain in human tumours. BMC cancer, 22(1), 498. 2. Wu, Z., Sun, S., Fan, R., & Wang, Z. (2022). Tubulin alpha 1c promotes aerobic glycolysis and cell growth through upregulation of yes association protein expression in breast cancer. Anti-Cancer Drugs, 33(2), 132-141. 3. Gui, S., Chen, P., Liu, Y., Chen, Q., Cheng, T., Lv, S., ... & Cheng, Z. (2021). TUBA1C expression promotes proliferation by regulating the cell cycle and indicates poor prognosis in glioma. Biochemical and biophysical research communications, 577, 130-138.

Uniprot ID: Q9BQE3

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 55 kDa

Calculated Molecular Weight: 50 kDa

Gene ID: 84790

Protein Name: Tubulin alpha-1C chain

Gene Full Name: tubulin alpha 1c

Synonyms: TUBA1C; TUBA6; Tubulin alpha-1C chain; Alpha-tubulin 6; Tubulin alpha-6 chain [Cleaved into: Detyrosinated tubulin alpha-1C chainz