ANKRD30A Polyclonal Antibody

SKU: BT-AP00453

Size:100μL

Background:Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD30A (ankyrin repeat domain 30A), also known as serologically defined breast cancer antigen NY-BR-1, is a 1,397 amino acid coiled-coil protein. Containing six ANK repeats and thirty-seven exons, ANKRD30A is a distant homolog of the POTE family. Initiated by either Dnmt1 or Met-57, ANKRD30A is highly expressed in breast and testis, and faintly in placenta. Present in 80% of breast cancers, but not in other types of tumors, ANKRD30A is a differentiation antigen and a potential target for antibody‐based therapies in breast cancers.

Research_area:Others

Target_protein:ANKRD30A

applications:WB, IHC-p, ELISA

Reactivity:Human

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:ANKRD30A Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):152674

UniProt accession:Human: Q9BXX3

Synonyms:ANKRD30A; Ankyrin repeat domain-containing protein 30A; Serologically defined breast cancer antigen NY-BR-1

GeneID:Human: 91074