ANKRD28 Antibody - Cat. #: CSB-PA929390

SKU: CSB-PA929390

Size :50ul

Clone Number:

Aliases:ANKRD28 antibody; KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody; PP6-ARS-A antibody; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody; Ankyrin repeat domain-containing protein 28 antibody; Phosphatase interactor targeting protein hnRNP K antibody; PITK antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15084

Immunogen:Synthetic peptide of Human ANKRD28

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ANKRD28

Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Signal transduction