ANGPTL4 Polyclonal antibody

SKU: AN006110L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:Angptl4

Target Synonym:ARP;Secreted protein Bk;Angiopoietin-like protein;Angiopoietin-related protein;ANGPTL;425O18;425O18-1;Angiopoietin-like protein 4;Angiopoietin-related protein 4;ARP4;Fasting-induced adipose factor;Hepatic fibrinogen/angiopoietin-related protein;HFARP;NL2;PGAR;pp1158;Secreted protein Bk89;Farp;Fiaf;Ng27;Angptl4

Research Areas:

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9Z1P8

Accession:

Background:Angiopoietin-related protein 4 (ANGPTL4) is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Concentration:1 mg/mL

Immunogen:Recombinant Mouse ANGPTL4 protein expressed by Mammalian

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1:1000

Calculated MW:45 kDa

ObservedMW:50 kDa