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GeneBio Systems

Amphiregulin Polyclonal Antibody

Amphiregulin Polyclonal Antibody

SKU:AN005810L

Regular price £109.00 GBP
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Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:Amphiregulin

Target Synonym:KAF;AREG;AR;AREGB;CRDGF;SDGF;amphiregulin;Colorectum Cell-Derived Growth Factor

Research Areas:Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P15514

Accession:

Background:The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.

Concentration:1 mg/mL

Immunogen:Recombinant Human Amphiregulin protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Antigen Affinity Purification

Dilution:IF 1:100-1:200

Calculated MW:

ObservedMW:

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