Amphiphysin II Polyclonal Antibody

SKU: E-AB-13951

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: BIN1

Target Synonym: AMPH 2;AMPH2;Amphiphysin 2;Amphiphysin II;Amphiphysin like protein;amphiphysin-like;Amphiphysin-like protein;AMPHL;Bin1;BIN1;Box Dependant MYC Interacting Protein 1;Box-dependent myc-interacting protein 1;Bridging integrator 1;DKFZp547F068;MGC10367;MGC105358;Myc box dependent interacting protein 1;Myc box-dependent-interacting protein 1;SH3P9

Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Microbiology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O00499

Accession:

Background: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Concentration: 0.1 mg/mL

Immunogen: Recombinant protein of human BIN1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: