Alpha-2-macroglobulin antibody , Cat. # FNab10346

SKU: FNab10346

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Alpha-2-macroglobulin, also known as ?2-macroglobulin(?2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.

Immunogen:alpha-2-macroglobulin

Synonyms:A2M, Alpha 2 M, alpha 2 macroglobulin, CPAMD5, DKFZp779B086, FWP007, S863 7, ?-2M

Observed MW:

Uniprot ID:P01023

Reactivity:Human

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20-1:200

Gene ID:2

Research Area:Immunology, Cardiovascular, Metabolism, Signal Transduction