ALOX5 Antibody - Cat. #: CSB-PA043268

SKU: CSB-PA043268

Size :50ul

Clone Number:

Aliases:5 Lipoxygenase antibody; 5 LO antibody; 5 LOX antibody; 5-lipoxygenase antibody; 5-LO antibody; 5-LOX antibody; 5LOX antibody; 5LPG antibody; ALOX 5 antibody; Alox5 antibody; Arachidonate 5 lipoxygenase antibody; Arachidonate 5-lipoxygenase antibody; arachidonic 5-lipoxygenase alpha-10 isoform antibody; arachidonic 5-lipoxygenase delta-10-13 isoform antibody; arachidonic 5-lipoxygenase delta-13 isoform antibody; arachidonic 5-lipoxygenase delta-p10 isoform antibody; Arachidonic acid 5 lipoxygenase antibody; Leukotriene A4 synthase antibody; LOG 5 antibody; LOG5 antibody; LOX5_HUMAN antibody; MGC163204 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P09917

Immunogen:Fusion protein of Human ALOX5

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:500-1:5000, IHC:1:50-1:150

Background:This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ALOX5

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction