AFF4 Antibody, HRP conjugated - Cat. #: CSB-PA890687LB01HU

SKU: CSB-PA890687LB01HU

Size :50ug

Clone Number:

Aliases:AFF4 antibody; AF5Q31 antibody; MCEF antibody; HSPC092 antibody; AF4/FMR2 family member 4 antibody; ALL1-fused gene from chromosome 5q31 protein antibody; Protein AF-5q31 antibody; Major CDK9 elongation factor-associated protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UHB7

Immunogen:Recombinant Human AF4/FMR2 family member 4 protein (77-334AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:AFF4

Research Areas:Epigenetics and Nuclear Signaling; Cell biology