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GeneBio Systems

ADH7 rabbit pAb

ADH7 rabbit pAb

SKU:ES1608

Regular price £281.00 GBP
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Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Monkey

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human ADH7. AA range:211-260

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):40kD

Human_gene_id:131

Human_swiss_prot_no:P40394

Subcellular_location:Cytoplasm.

Other_name:ADH7; Alcohol dehydrogenase class 4 mu/sigma chain; Alcohol dehydrogenase class IV mu/sigma chain; Gastric alcohol dehydrogenase; Retinol dehydrogenase

Background:This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

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