ACVR1C antibody , Cat. # FNab00130

SKU: FNab00130

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)

Background:ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

Immunogen:activin A receptor, type IC

Synonyms:ACVR1C, Activin receptor type 1C, Activin receptor type IC, ACVRLK7, ALK 7

Observed MW:60 kDa

Uniprot ID:Q8NER5

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Gene ID:130399

Research Area:Stem Cells, Signal Transduction, Metabolism