Acetyl P53(K382) (1G7) Mouse mAb

SKU: EM1382

Size: 100μL

Source:Mouse

Applications:IHC

Reactivity:Human, Mouse, Rat

Dilution:IHC 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):53kDa

Human_gene_id:7157

Human_swiss_prot_no:P04637

Subcellular_location:Cytoplasm,Cytoplasm. Nucleus

Other_name:Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody

Background:p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. Acetylation appears to play a positive role in the accumulation of p53 protein in stress response.