ABL2 Monoclonal Antibody

SKU: BT-MCA2478

Size:100μL

Background:ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.

Research_area:Signal Transduction

Target_protein:ABL2

applications:ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:1H1B11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ABL2

Immunogen:Purified recombinant fragment of ABL2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P42684

Synonyms:ARG, ABLL, FLJ22224, FLJ31718, FLJ41441

GeneID:27