Aβ40 Polyclonal Antibody

SKU: E-AB-40070

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: Aβ40

Target Synonym: A4 amyloid protein;A4;AAA;ABETA;ABPP;AD1;AICD-50;AICD-57;AICD-59;AID(50);AID(57);AID(59);Alzheimer disease amyloid protein;Amyloid beta (A4) precursor protein;Amyloid beta A4 protein;Amyloid beta protein;Amyloid intracellular domain 50;Amyloid intracellular domain 57;Amyloid intracellular domain 59;Amyloid precursor protein;APP;APPI;Beta amyloid peptide;Beta-amyloid precursor protein;Beta-APP40;Beta-APP42;C31;Cerebral vascular amyloid peptide;CTFgamma;CVAP;Gamma-CTF(50);Gamma-CTF(57);Gamma-CTF(59);peptidase nexin II;PN 2;PN II;PN-II;PN2;PreA4;Protease nexin II;Protease nexin-II;S-APP-alpha;S-APP-beta

Research Areas: Cancer;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P12023

Accession:

Background: Aβ derives from APP via proteolytic cleavage by proteases called α-, β- and γ-secretase. The α-secretase cleavage precludes the formation of Aβ, while the β- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1). This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.

Concentration: 1 mg/mL

Immunogen: Recombinant Mouse Beta-amyloid 40 protein

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: IHC 1:50-1:100

Calculated MW:

ObservedMW: