Recombinant Escherichia coli GTP cyclohydrolase-2(ribA)

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Recombinant Escherichia coli GTP cyclohydrolase-2(ribA)

CSB-RP167474Ba
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Size: 200ug. Other sizes are also available. Please Inquire.

In Stock: No

Lead time: 10-20 working days

Research Topic: Others

Uniprot ID: P0A7I7

Gene Names: ribA

Organism: Escherichia coli (strain K12)

AA Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK

Expression Region: 1-196aa

Sequence Info: Full Length

Source: E.coli

Tag Info: N-terminal 6xHis-tagged

MW: 25.8 kDa

Alternative Name(s): GTP cyclohydrolase II

Relevance: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

Reference: Biosynthesis of riboflavin studies on the mechanism of GTP cyclohydrolase II.Ritz H., Schramek N., Bracher A., Herz S., Eisenreich W., Richter G., Bacher A.J. Biol. Chem. 276:22273-22277(2001)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage Buffer: Tris-based buffer,50% glycerol

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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