YBX1 Polyclonal Antibody

SKU: E-AB-53542

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:YBX1

Target Synonym:BP 8;CBF-A;CCAAT binding transcription factor I subunit A;CCAAT-binding transcription factor I subunit A;CSDA2;CSDB;DBPB;DNA binding protein B;DNA-binding protein B;EFI-A;Enhancer factor I subunit A;MDR NF1;MGC104858;MGC110976;MGC117250;NSEP 1;NSEP1;Nuclease sensitive element binding protein 1;Nuclease-sensitive element-binding protein 1;p50;Q15905;Y-box binding protein 1;Y-box transcription factor;Y-box-binding protein 1;YB 1;YB-1;YBOX1;YBX 1;ybx1

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Developmental Biology;Stem Cells;Tags and Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P67809

Accession:

Background:This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).

Concentration:0.6 mg/mL

Immunogen:Synthetic peptide of human YBX1

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:30-1:150

Calculated MW:

ObservedMW: