YAP(Phospho Ser127) Polyclonal Antibody

SKU: BT-AP15585

Size:100μL

Background:This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research_area:Epigenetics and nuclear signaling; Cancer; Signal transduction

Target_protein:YAP1

applications:IF, ICC, WB, IHC-p, ELISA

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Yorkie homolog

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):48755

UniProt accession:Human: P46937; Mouse: P46938; Rat: Q2EJA0

Synonyms:Yorkie homolog; YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

GeneID:Human: 10413; Mouse: 22601; Rat: 363014