XPC Rabbit Polyclonal Antibody

SKU: BT-AP05520

Size:100μL

Background:This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway| including Xeroderma pigmentosum (XP) A-G and V| Cockayne syndrome (CS) A and B| and trichothiodystrophy (TTD) group A| etc. This component| XPC| plays an important role in the early steps of global genome NER| especially in damage recognition| open complex formation| and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum| a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:XPC

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:XPC

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):103400

UniProt accession:Human: Q01831; Mouse: P51612

Synonyms:XPC

GeneID:Human: 7508; Mouse: 22591