WNT1 Monoclonal Antibody

SKU: BT-MCA2624

Size:100μL

Background:WNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Research_area:Stem Cells

Target_protein:WNT1

applications:WB, IHC, ICC, FCM

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:10C8

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:WNT1

Immunogen:Purified recombinant fragment of WNT1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):41kDa

UniProt accession:P04628

Synonyms:INT1

GeneID:7471