Gene Bio Systems
WDYHV1 Antibody, FITC conjugated - Cat. #: CSB-PA850306LC01HU
WDYHV1 Antibody, FITC conjugated - Cat. #: CSB-PA850306LC01HU
SKU:CSB-PA850306LC01HU
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Size :50ug
Clone Number:
Aliases:WDYHV1 antibody; C8orf32 antibody; NTAQ1 antibody; Protein N-terminal glutamine amidohydrolase antibody; EC 3.5.1.122 antibody; Protein NH2-terminal glutamine deamidase antibody; N-terminal Gln amidase antibody; Nt(Q)-amidase antibody; WDYHV motif-containing protein 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q96HA8
Immunogen:Recombinant Human Protein N-terminal glutamine amidohydrolase protein (1-205AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:
Background:Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:WDYHV1
Research Areas:Cell biology
