WDR83 Antibody - Cat. #: CSB-PA863110LA01HU

SKU: CSB-PA863110LA01HU

Size :50ul

Clone Number:

Aliases:MAPK organizer 1 antibody; MGC4238 antibody; Mitogen activated protein kinase organizer 1 antibody; Mitogen-activated protein kinase organizer 1 antibody; MORG 1 antibody; WD repeat domain-containing protein 83 antibody; wdr83 antibody; WDR83_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BRX9

Immunogen:Recombinant Human WD repeat domain-containing protein 83 protein (64-315AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background:Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:WDR83

Research Areas:Epigenetics and Nuclear Signaling; Cardiovascular; Signal transduction