VWF rabbit pAb

SKU: ES10984

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human;Rat;Mouse

Dilution:IHC-p 1:50-300

Immunogen:Synthesized peptide derived from part region of human protein AA range: 911-960

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):309kD

Human_gene_id:7450

Human_swiss_prot_no:P04275

Subcellular_location:Secreted . Secreted, extracellular space, extracellular matrix . Localized to storage granules.

Other_name:

Background:This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015],