VPS4B Antibody - Cat. #: CSB-PA808620

SKU: CSB-PA808620

Size :50ul

Clone Number:

Aliases:vacuolar protein sorting 4 homolog B (S. cerevisiae)

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75351

Immunogen:Synthetic peptide of Human VPS4B

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50

Background:The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:VPS4B

Research Areas:Signal transduction