VATE1 Rabbit Polyclonal Antibody

SKU: BT-AP05437

Size:100μL

Background:This gene encodes a component of vacuolar ATPase (V-ATPase)| a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting| zymogen activation| receptor-mediated endocytosis| and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A| three B| and two G subunits| as well as a C| D| E| F| and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants| encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

Research_area:Signal transduction; Metabolism

Target_protein:ATP6V1E1

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:VATE1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):24860

UniProt accession:Human: P36543; Mouse: P50518; Rat: Q6PCU2

Synonyms:VATE1

GeneID:Human: 529; Mouse: 11973; Rat: 297566