VASP Monoclonal Antibody

SKU: BT-MCA2964

Size:100μL

Background:Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]

Research_area:Signal Transduction

Target_protein:VASP

applications:WB, IHC, ICC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:6B10A1

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:VASP

Immunogen:Purified recombinant fragment of human VASP (AA: 1-380) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):39.8kDa

UniProt accession:P50552

Synonyms:

GeneID:7408