V-ATPase C2 Polyclonal Antibody

SKU: BT-AP09481

Size:100μL

Background:ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1C2 encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.

Research_area:Signal Transduction; Metabolism

Target_protein:ATP6V1C2

applications:WB, ELISA

Reactivity:Human

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:V-ATPase C2 Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):48759

UniProt accession:Human: Q8NEY4; Mouse: Q99L60

Synonyms:ATP6V1C2; V-type proton ATPase subunit C 2; V-ATPase subunit C 2; Vacuolar proton pump subunit C 2

GeneID:Human: 245973