UBP14 Polyclonal Antibody

SKU: BT-AP15317

Size:100μL

Background:This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research_area:Cell biology; Epigenetics and nuclear signaling

Target_protein:USP14

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Ubiquitin carboxyl-terminal hydrolase 14

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P54578; Mouse: Q9JMA1

Synonyms:Ubiquitin carboxyl-terminal hydrolase 14 ;EC 3.4.19.12;Deubiquitinating enzyme 14;Ubiquitin thioesterase 14;Ubiquitin-specific-processing protease 14

GeneID:Human: 9097