TSLPR Monoclonal Antibody

SKU: BT-MCA3174

Size:100μL

Background:This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Research_area:Others

Target_protein:TSLPR

applications:IHC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:1E10D3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:TSLPR

Immunogen:Purified recombinant fragment of human TSLPR (AA: extra(23-231)) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):42kDa

UniProt accession:Q9HC73

Synonyms:CRL2, TSLPR, CRLF2Y

GeneID:64109