GeneBio Systems
TRPC6 rabbit pAb
TRPC6 rabbit pAb
SKU:ES12548
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Size: 100μL
Source:Rabbit
Applications:WB
Reactivity:Human; Mouse
Dilution:WB 1:500-2000
Immunogen:Synthesized peptide derived from human TRPC6 AA range: 412-462
Storage_stability:-20°C/1 year
Clonality:Polyclonal
Isotype:IgG
Concentration:1 mg/ml
Observed_band(KD):
Human_gene_id:7225
Human_swiss_prot_no:Q9Y210
Subcellular_location:Cell membrane ; Multi-pass membrane protein .
Other_name:
Background:The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009],
