TOPRS Polyclonal Antibody

SKU: BT-AP15076

Size:100μL

Background:This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.

Research_area:Epigenetics and nuclear signaling; Cancer

Target_protein:TOPORS

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:E3 ubiquitin-protein ligase Topors

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9NS56; Mouse: Q80Z37

Synonyms:E3 ubiquitin-protein ligase Topors ;EC 6.3.2.-;SUMO1-protein E3 ligase Topors;Topoisomerase I-binding RING finger protein;Topoisomerase I-binding arginine/serine-rich protein;Tumor suppressor

GeneID:Human: 10210