TNFRSF1B Antibody - Cat. #: CSB-PA234429

SKU: CSB-PA234429

Size :50ul

Clone Number:

Aliases:CD120b antibody; p75 antibody; p75 TNF receptor antibody; p75TNFR antibody; p80 TNF alpha receptor antibody; p80 TNF-alpha receptor antibody; Soluble TNFR1B variant 1 antibody; TBP-2 antibody; TBPII antibody; TNF R II antibody; TNF R2 antibody; TNF R75 antibody; TNF-R2 antibody; TNF-RII antibody; TNFBR antibody; TNFR-II antibody; TNFR1B antibody; TNFR2 antibody; TNFR80 antibody; TNFRII antibody; Tnfrsf1b antibody; TNR1B_HUMAN antibody; Tumor necrosis factor beta receptor antibody; Tumor necrosis factor binding protein 2 antibody; Tumor necrosis factor receptor 2 antibody; Tumor necrosis factor receptor superfamily member 1B antibody; Tumor necrosis factor receptor type II antibody; Tumor necrosis factor-binding protein 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P20333

Immunogen:Fusion protein of Human TNFRSF1B

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNFRSF1B

Research Areas:Cancer;Cell biology;Immunology;Signal transduction