TEAD4 Antibody, FITC conjugated - Cat. #: CSB-PA618010LC01HU

SKU: CSB-PA618010LC01HU

Size :50ug

Clone Number:

Aliases:EFTR 2 antibody; EFTR2 antibody; hRTEF 1B antibody; hRTEF1B antibody; MGC9014 antibody; OTTHUMP00000238119 antibody; OTTHUMP00000238122 antibody; OTTHUMP00000238124 antibody; Related to TEF 1 antibody; Related to TEF1 antibody; Related transcription enhancer factor 1B antibody; RTEF1 antibody; TCF13L1 antibody; TEA domain family member 4 antibody; TEAD 4 antibody; TEAD-4 antibody; TEAD4 antibody; TEAD4_HUMAN antibody; TEF 3 antibody; TEF3 antibody; TEFR 1 antibody; TEFR1 antibody; Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody; Transcription factor 13 like 1 antibody; Transcription factor 13-like 1 antibody; Transcription factor RTEF 1 antibody; Transcription factor RTEF-1 antibody; Transcription factor RTEF1 antibody; Transcriptional enhancer factor 1 related antibody; Transcriptional enhancer factor 3 antibody; Transcriptional enhancer factor TEF 3 antibody; Transcriptional enhancer factor TEF-3 antibody; Transcriptional enhancer factor TEF3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15561

Immunogen:Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC \'enhansons\' (5\'-GTGGAATGT-3\') and activates transcription. Binds to the M-CAT motif.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TEAD4

Research Areas:Epigenetics and Nuclear Signaling; Cardiovascular